N,N'-Dimethylethylenediamine → HCID 89691284, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-((4-fluorobenzyl)oxy)pyridin-2(1H)-one (91 mg), 6-bromo-2-(cyclopropylmethyl)-1-methyl-1H-benzimidazole (165 mg), N,N′-dimethylethylenediamine (0.045 ml)-, copper iodide (79 mg), potassium carbonate (229 mg) and DMSO (3 ml) was heated at 150° C. for 2 h under microwave irradiation. After cooling, the reaction mixture was purified by NH silica gel column chromatography (hexane/EtOAc to MeOH/EtOAc). The resulting solid was washed with EtOAc and dried to give the title compound (62 mg) as a pale yellow solid.

Provenance & Evidence