HCID 21995030, compound → 5,7-Dimethoxy-N-methyl-1H-benzimidazole-2-propanamine

HRID 220288Notes

Reaction equation

HRID 220288 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[C:5]([NH2:11])[C:4]=1[NH2:12].CO[C:15]1C(OC)=C[C:18]2[NH:19][C:20](CCCNC)=N[C:17]=2[CH:16]=1>>[CH3:1][O:2][C:3]1[C:4]2[N:12]=[C:15]([CH2:16][CH2:17][CH2:18][NH:19][CH3:20])[NH:11][C:5]=2[CH:6]=[C:7]([O:9][CH3:10])[CH:8]=1

Participants

3

Reactant 2

HCID 21995030HCID 21995030, compoundHCID 61363740[3-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amine

Product 1

HCID 684128665,7-Dimethoxy-N-methyl-1H-benzimidazole-2-propanamine

Procedure

Prepared from 3,5-dimethoxy-benzene-1,2-diamine in analogy to the methods described for [3-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amine.

Sources & evidence

ORD record
ord-4cf72697498c4dacb934b1e0a3a59c94
Source dataset
uspto-grants-2012_06
Patent number
US08202885B2

Reaction notes

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