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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 220289Generated: October 25, 2026

1-Phenyl-1,2-propanedione → 3-[4-Methyl-5-phenyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-propionic acid

https://huagongshe.com/reaction/220289

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Phenyl-1,2-propanedioneHCID 11363—
Reactant3-[4,5-diphenyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-propionic acidHCID 68414372—
Product3-[4-Methyl-5-phenyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-propionic acidHCID 68412504—

Reaction Steps

Prepared in analogy to the methods described for 3-[4,5-diphenyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-propionic acid replacing benzil with 1-phenyl-propane-1,2-dione.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08202885B2
Source datasetuspto-grants-2012_06
ORD IDord-f4478e32d21b4b76bfc6bb5ac490f448
Source noteuspto-grants-2012_06