HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2202969Generated: October 31, 2026
N,N'-Dimethylethylenediamine → HCID 89690578, compound
https://huagongshe.com/reaction/2202969
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,N'-Dimethylethylenediamine | HCID 8070 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Benzyloxy-2(1H)-pyridone | HCID 3607724 | — |
| Reactant | 5-bromo-N-methyl-2-nitroaniline | HCID 10609530 | — |
| Catalyst | Copper iodide | HCID 83717 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 89690578 | HCID 89690578 | 58.4% |
Reaction Steps
The mixture of 4-(benzyloxy)pyridin-2(1H)-one (5.0 g), 5-bromo-N-methyl-2-nitroaniline (5.74 g), copper iodide (4.73 g), N,N′-dimethylethylenediamine (2.8 ml) and potassium carbonate (10.30 g) in DMSO (250 ml) was stirred at 150° C. under N2 for 1 h. After cooling to room temperature, 28% NH3solution was added to the resulting mixture. The resulting suspension was filtered. The precipitate was washed with water and IPA and dried to give the title compound (5.1 g) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09365540B2 |
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| Source dataset | uspto-grants-2016_06 |
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| ORD ID | ord-a6de4db3ae9d4ecba18647ff97cd2bc3 |
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| Source note | uspto-grants-2016_06 |
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