HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3,3-Trifluoropropionyl chloride → rac-3,3,3-Trifluoro-propionic acid (1R*,5R*,6R*)-6-(2-{[3-(4-methoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-8-phenyl-bicyclo[3.2.2]non-8-en-6-yl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3,3-Trifluoropropionyl chloride | HCID 2783343 | — |
| Reactant | rac-(1R*,5R*,6R*)-6-(2-{[3-(4-methoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-8-phenyl-bicyclo[3.2.2]non-8-en-6-ol | HCID 68413373 | — |
| Product | rac-3,3,3-Trifluoro-propionic acid (1R*,5R*,6R*)-6-(2-{[3-(4-methoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-8-phenyl-bicyclo[3.2.2]non-8-en-6-yl ester | HCID 91573175 | — |
Reaction Steps
Prepared according to procedure P1.4 in Example 1A using 3,3,3-trifluoropropionyl chloride and rac-(1R*,5R*,6R*)-6-(2-{[3-(4-methoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-8-phenyl-bicyclo[3.2.2]non-8-en-6-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08202885B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-1550fa7211ef471fa375c38bae2e077a |
| Source note | uspto-grants-2012_06 |