Azobisisobutyronitrile → HCID 89690256, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-methyl-5-(trifluoromethyl)pyrazine (1 g) in trifluoromethylbenzene (10 ml) was added N-bromosuccinimide (1.21 g) at room temperature, and the mixture was heated at 90° C. for 30 min. To the mixture was then added azobisisobutyronitrile (0.051 g), and the mixture was stirred for 7 h. The mixture was cooled, and the solvent was evaporated. The residue was purified by column chromatography (hexane/EtOAc) to give the title compound (404 mg) as a pale yellow oil.

Provenance & Evidence