Ammonium Chloride → HCID 89690257, compound

Participants

Reaction Steps

To a solution of ethyl 4-cyano-1,3-thiazole-2-carboxylate (336 mg) in MeOH (10 ml) was added NaBH4 (140 mg), and the mixture was stirred at room temperature for 3 h. The mixture was poured into saturated NH4Cl solution, concentrated in vacuo, and extracted with EtOAc. The extract was washed with brine, dried over MgSO4, and concentrated in vacuo to give the title compound (253 mg) as a yellow oil.

Provenance & Evidence