Ammonium Chloride → HCID 89690274, compound

Participants

Reaction Steps

To a solution of ethyl 4-(fluoromethyl)-1,3-thiazole-2-carboxylate (170 mg) in MeOH (5 ml) was added NaBH4 (68 mg), and the mixture was stirred at room temperature for 3 h. The mixture was poured into saturated NH4Cl solution, and extracted with EtOAc. The extract was washed with brine, dried over MgSO4, and concentrated in vacuo to give the title compound (114 mg) as a colorless oil.

Provenance & Evidence