2-amino-5-(trifluoromethoxy)benzoic Acid → Methyl 2-amino-5-(trifluoromethoxy)benzoate

HRID 2203153Notes

Reaction equation

HRID 2203153 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][C:9](C(F)(F)F)=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].NC1C=CC([O:26][C:27]([F:30])([F:29])[F:28])=CC=1C(O)=O>>[NH2:1][C:2]1[CH:11]=[CH:10][C:9]([O:26][C:27]([F:30])([F:29])[F:28])=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5]

Participants

3

Reactant 2

HCID 110853492-amino-5-(trifluoromethoxy)benzoic AcidHCID 14233808Methyl 2-amino-5-(trifluoromethyl)benzoate

Product 1

HCID 18669299Methyl 2-amino-5-(trifluoromethoxy)benzoate

Procedure

The title compound was prepared as in the method of compound 1 from 2-amino-5-(trifluoromethoxy)benzoic acid to give a pale yellow oil (0.538 g, 46%).

Sources & evidence

ORD record
ord-9323b13500274987a8613c4030f49927
Source dataset
uspto-grants-2016_06
Patent number
US09365569B2

Reaction notes

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