Methyl 2-amino-5-(trifluoromethoxy)benzoate → Methyl 2-amino-3-iodo-5-(trifluoromethoxy)benzoate

HRID 2203154Notes

Reaction equation

HRID 2203154 reaction equation
[NH2:1][C:2]1[C:11]([I:12])=[CH:10][C:9](C(F)(F)F)=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].NC1C=CC([O:28][C:29]([F:32])([F:31])[F:30])=CC=1C(OC)=O>>[NH2:1][C:2]1[C:11]([I:12])=[CH:10][C:9]([O:28][C:29]([F:32])([F:31])[F:30])=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5]

Participants

3

Reactant 2

HCID 18669299Methyl 2-amino-5-(trifluoromethoxy)benzoateHCID 118251642Methyl 2-amino-3-iodo-5-(trifluoromethyl)benzoate

Product 1

HCID 118251594Methyl 2-amino-3-iodo-5-(trifluoromethoxy)benzoate

Procedure

The title compound was prepared as in the method of compound 2 from methyl 2-amino-5-(trifluoromethoxy)benzoate to give a white solid (0.67 g, 82%).

Sources & evidence

ORD record
ord-10edfa2e8f0c41928c1d1ffa96e595ac
Source dataset
uspto-grants-2016_06
Patent number
US09365569B2

Reaction notes

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