Methyl 2-amino-3-iodo-5-(trifluoromethoxy)benzoate → Methyl 2-amino-3-methyl-5-(trifluoromethoxy)benzoate

HRID 2203155Notes

Reaction equation

HRID 2203155 reaction equation
[NH2:1][C:2]1[C:11]([CH3:12])=[CH:10][C:9](C(F)(F)F)=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].NC1C(I)=CC([O:29][C:30]([F:33])([F:32])[F:31])=CC=1C(OC)=O>>[NH2:1][C:2]1[C:11]([CH3:12])=[CH:10][C:9]([O:29][C:30]([F:33])([F:32])[F:31])=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5]

Participants

3

Reactant 2

HCID 118251594Methyl 2-amino-3-iodo-5-(trifluoromethoxy)benzoateHCID 118251663Methyl 2-amino-3-methyl-5-(trifluoromethyl)benzoate

Product 1

HCID 118251634Methyl 2-amino-3-methyl-5-(trifluoromethoxy)benzoate

Procedure

The title compound was prepared as in the method of compound 3 from methyl 2-amino-3-iodo-5-(trifluoromethoxy)benzoate to give an orange oil (0.413 g, 89%).

Sources & evidence

ORD record
ord-78cdc701f2fe4c7abc3f07578ebec286
Source dataset
uspto-grants-2016_06
Patent number
US09365569B2

Reaction notes

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