Isobutyl iodide → HCID 118251639, compound

HRID 2203158Notes

Reaction equation

[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([Br:14])[CH:8]=[C:9]2[C:13]=1[NH:12][N:11]=[CH:10]2)=[O:4].I[CH2:16][CH:17]([CH3:19])[CH3:18]>>[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([Br:14])[CH:8]=[C:9]2[C:13]=1[N:12]([CH2:16][CH:17]([CH3:19])[CH3:18])[N:11]=[CH:10]2)=[O:4]

Participants

Reactant 2

HCID 10556Isobutyl iodide

HCID 24728927Methyl 5-bromo-1H-indazole-7-carboxylate

Product 1

HCID 118251639HCID 118251639, compoundYield 70%

Procedure

Compound 10 was prepared following general method 1, using 5-bromo-1H-indazole-7-carboxylic acid methyl ester as starting material and 1-iodo-2-methylpropane as alkylating agent. Yield: 70%.

Sources & evidence

ORD record: ord-a25b0e820bf04ed79002f6b8f142ed2b
Source dataset: uspto-grants-2016_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09365569B2

Reaction notes

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