Isopropyl iodide → HCID 118251657, compound

HRID 2203162Notes

Reaction equation

HRID 2203162 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([Br:14])[CH:8]=[C:9]2[C:13]=1[NH:12][N:11]=[CH:10]2)=[O:4].I[CH:16]([CH3:18])[CH3:17]>>[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([Br:14])[CH:8]=[C:9]2[C:13]=1[N:12]([CH:16]([CH3:18])[CH3:17])[N:11]=[CH:10]2)=[O:4]

Participants

3

Reactant 2

HCID 6362Isopropyl iodideHCID 24728927Methyl 5-bromo-1H-indazole-7-carboxylate

Product 1

HCID 118251657HCID 118251657, compoundYield 65%

Procedure

Compound 14 was prepared following general method 1, using 5-bromo-1H-indazole-7-carboxylic acid methyl ester as a starting material and 2-iodopropane as alkylating agent. Yield: 65%.

Sources & evidence

ORD record
ord-e62e5e39766143ecbf261cd30c2b56ba
Source dataset
uspto-grants-2016_06
Patent number
US09365569B2

Reaction notes

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