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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2203165Generated: November 1, 2026

Methyl 1H-indazole-5-carboxylate → 1-(5-Chloro-1-isobutyl-1H-indazol-7-ylmethyl)-1H-indazole-5-carboxylic acid methyl ester

https://huagongshe.com/reaction/2203165

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 1H-indazole-5-carboxylateHCID 22260640—
Reactant(5-Chloro-1-isobutyl-1H-indazole-7-yl)-methanolHCID 118251601—
Product1-(5-Chloro-1-isobutyl-1H-indazol-7-ylmethyl)-1H-indazole-5-carboxylic acid methyl esterHCID 11825165640%

Reaction Steps

Compound 25 was prepared following general method 3A, using compound 17 as a starting material and 1H-indazole-5-carboxylic acid methyl ester as the heterocycle. Yield: 40%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09365569B2
Source datasetuspto-grants-2016_06
ORD IDord-e8d0397ebc1d4cffb8960de089a9b287
Source noteuspto-grants-2016_06