HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 1H-pyrazolo[3,4-b]pyridine-5-carboxylate → 1-(5-Chloro-1-isobutyl-1H-indazol-7-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 1H-pyrazolo[3,4-b]pyridine-5-carboxylate | HCID 57415679 | — |
| Reactant | (5-Chloro-1-isobutyl-1H-indazole-7-yl)-methanol | HCID 118251601 | — |
| Product | 1-(5-Chloro-1-isobutyl-1H-indazol-7-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid methyl ester | HCID 118251670 | 53% |
Reaction Steps
Compound 33 was prepared following general method 3A, using compound 17 as a starting material and 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid methyl ester as the heterocycle. Yield: 53%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365569B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-cf28aaf42c4344afab512c9d18c223ae |
| Source note | uspto-grants-2016_06 |