HuagongsheHuagongshe Chemistry Print Report · For research reference only
[3-(4-chloro-1H-benzoimidazol-2-yl)-propyl]methyl-amine → rac-(1R*,2R*,4R*)-2-(2-{[3-(4-Chloro-1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-5-phenyl-bicyclo[2.2.2]oct-5-en-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [3-(4-chloro-1H-benzoimidazol-2-yl)-propyl]methyl-amine | HCID 60787078 | — |
| Reactant | HCID 66878002 | HCID 66878002 | — |
| Product | rac-(1R*,2R*,4R*)-2-(2-{[3-(4-Chloro-1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-5-phenyl-bicyclo[2.2.2]oct-5-en-2-ol | HCID 68415466 | — |
Reaction Steps
Prepared according to procedures P2.2 to P2.3 in Example 21 using rac-(1R*,2R*,4R*)-(2-hydroxy-5-phenyl-bicyclo[2.2.2]oct-5-en-2-yl)-acetic acid and [3-(4-chloro-1H-benzoimidazol-2-yl)-propyl]methyl-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08202885B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-ff45ae2c33914e36967b7a75663f0681 |
| Source note | uspto-grants-2012_06 |