Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 90426660 | HCID 90426660 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 90426456 | HCID 90426456 | 40% |
Reaction Steps
To a solution of 7-bromo-2,6-dimethyl-2H-indazole (1 equiv.) in NMP, was added CuCN (2 equiv.) and heated at 130° C. for 16 h. On completion, water was added to quench the reaction, solid precipitated was filtered and purified by column chromatography to afford the title compound (40-60% yield)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09365570B2 |
|---|
| Source dataset | uspto-grants-2016_06 |
|---|
| ORD ID | ord-ad3cdccd8ed444088f381a0467ba8f57 |
|---|
| Source note | uspto-grants-2016_06 |
|---|
