HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(4-Fluoro-2-methylphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-Fluoro-2-methylaniline | HCID 67982 | — |
| Product | N-(4-Fluoro-2-methylphenyl)acetamide | HCID 2737623 | 74% |
Reaction Steps
A mixture of 4-fluoro-2-methylaniline (20 g) and (CH3CO)2O (400 mL) was stirred at RT for 3 hours. The reaction mixture was subsequently poured into ice water (1000 mL), stirred for 10 minutes, filtered, and dried under vacuum to give the title compound (20 g, 74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365566B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-259c4edab98645ea991b35ce6b268676 |
| Source note | uspto-grants-2016_06 |