(2-Oxo-2,3-dihydro-1H-indol-5-yl)boronic acid → HCID 89825245, compound

HRID 2203224Notes

Reaction equation

HRID 2203224 reaction equation
[O:1]=[C:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7](B(O)O)[CH:8]=2)[NH:3]1.[NH2:14][C:15]1[C:24]2[C:19](=[C:20](Br)[CH:21]=[CH:22][CH:23]=2)[N:18]=[N:17][C:16]=1[C:26]([NH2:28])=[O:27]>>[NH2:14][C:15]1[C:24]2[C:19](=[C:20]([C:6]3[CH:5]=[C:4]4[C:9]([CH2:10][C:2](=[O:1])[NH:3]4)=[CH:8][CH:7]=3)[CH:21]=[CH:22][CH:23]=2)[N:18]=[N:17][C:16]=1[C:26]([NH2:28])=[O:27]

Participants

3

Reactant 2

HCID 54595690(2-Oxo-2,3-dihydro-1H-indol-5-yl)boronic acidHCID 69905525HCID 69905525, compound

Product 1

HCID 89825245HCID 89825245, compound

Procedure

The title compound was prepared in a manner similar to EXAMPLE 1 using 2-oxoindolin-5-ylboronic acid and 4-amino-8-bromocinnoline-3-carboxamide. ESI-MS m/z [M+H]+ 320.2.

Sources & evidence

ORD record
ord-2d12e4fdd0074d609672bb52d519e2fb
Source dataset
uspto-grants-2016_06
Patent number
US09365566B2

Reaction notes

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