HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline → 4-Amino-8-(isoquinolin-7-yl)-7-methylcinnoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline | HCID 25104972 | — |
| Reactant | 4-Amino-8-bromo-7-methylcinnoline-3-carboxamide | HCID 89825213 | — |
| Product | 4-Amino-8-(isoquinolin-7-yl)-7-methylcinnoline-3-carboxamide | HCID 71765586 | — |
Reaction Steps
The title compound was prepared in a manner similar to EXAMPLE 1 using 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline and 4-amino-8-bromo-7-methylcinnoline-3-carboxamide. 1H NMR (500 MHz, CD3OD) δ ppm 2.30-2.36 (m, 3 H), 7.72-7.79 (m, 2 H), 7.94 (d, J=5.86 Hz, 1 H), 8.07-8.14 (m, 2 H), 8.22-8.31 (m, 1 H), 8.46-8.52 (m, 1 H), 9.29 (s, 1 H); ESI-MS m/z [M+H]+ 330.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365566B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-339f0c7bd51845e79c1c0c695f0fb35f |
| Source note | uspto-grants-2016_06 |