HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Isoquinolin-6-yl)boronic acid → 4-Amino-8-(isoquinolin-6-yl)-7-methylcinnoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Isoquinolin-6-yl)boronic acid | HCID 44119669 | — |
| Reactant | 4-Amino-8-bromo-7-methylcinnoline-3-carboxamide | HCID 89825213 | — |
| Product | 4-Amino-8-(isoquinolin-6-yl)-7-methylcinnoline-3-carboxamide | HCID 71765546 | — |
Reaction Steps
The title compound was prepared in a manner similar to EXAMPLE 1 using isoquinolin-6-ylboronic acid and 4-amino-8-bromo-7-methylcinnoline-3-carboxamide. 1H NMR (500 MHz, CD3OD) δ ppm 2.34 (s, 3 H), 7.67 (d, J=8.30 Hz, 1 H), 7.76 (d, J=8.79 Hz, 1 H), 7.90 (d, J=5.86 Hz, 1 H), 7.94 (s, 1 H), 8.28 (t, J=8.30 Hz, 2 H), 8.50 (d, J=5.86 Hz, 1H), 9.35 (s, 1 H); ESI-MS m/z [M+H]+ 330.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365566B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-4a5336d5030d43db8c321ccce177a0ad |
| Source note | uspto-grants-2016_06 |