HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indazole-5-boronic acid → 4-amino-5-fluoro-8-(1H-indazol-5-yl)-7-methylcinnoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indazole-5-boronic acid | HCID 17750504 | — |
| Reactant | 4-Amino-8-bromo-5-fluoro-7-methylcinnoline-3-carboxamide | HCID 89825462 | — |
| Product | 4-amino-5-fluoro-8-(1H-indazol-5-yl)-7-methylcinnoline-3-carboxamide | HCID 71765623 | — |
Reaction Steps
The title compound was prepared in a manner similar to EXAMPLE 1 using (1H-indazol-5-yl)boronic acid and 4-amino-8-bromo-5-fluoro-7-methylcinnoline-3-carboxamide. 1H NMR (400 MHz, CD3OD) δ ppm 2.28 (s, 3 H), 7.19-7.30 (m, 1 H), 7.35 (d, J=16 Hz, 1H), 7.59-7.70 (m, 2 H), 8.07 (s, 1 H); ESI-MS m/z [M+H]+ 337.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365566B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-fd31805896584bda911209732ebfcc32 |
| Source note | uspto-grants-2016_06 |