Cerate(2-), hexakis(nitrato-kappaO)-, potassium (1:2), (OC-6-11)- → HCID 90077560, compound

Participants

Reaction Steps

2-(4-(9-chloro-3-(4-methoxybenzyl)-2,4-dioxo-3,4-dihydropyrimidino[5,4-c][1,5]naphthyridine-1(2H)-yl)phenyl)-2-methylpropanenitrile (1.2 g, 2.3 mmol) was dissolved in acetonitrile (80 mL) and water (20 mL). Ammonium ceric nitrate (5.1 g, 9.4 mmol) was added in batch at room temperature. The reaction mixture was reacted at room temperature for 16 hrs, and then concentrated. 100 mL water was added. The mixture was filtered. The resulting solid was washed with EA and PE (1:1), and dried in vacuum to obtain a yellow solid (600 mg).

Provenance & Evidence