HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azobisisobutyronitrile → HCID 67996613, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | methyl 2-(pyrazin-2-yl)propanoate | HCID 63968586 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | HCID 67996613 | HCID 67996613 | — |
Reaction Steps
A carbon tetrachloride (150 mL) solution containing the intermediate from Step B (18 g, 108 mmol), N-bromosuccinimide (26.6 g, 150 mmol) and AIBN (0.5 g) was heated at reflux overnight. The solution was cooled to room temperature, filtered and concentrated. The residue was purified by silica gel chromatography using a hexanes/EtOAc gradient to give the indicated product. m/z=245.1 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365574B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-531f5a0296e44b3f89ecdeabe25e1dcf |
| Source note | uspto-grants-2016_06 |