Azobisisobutyronitrile → HCID 86678960, compound

Participants

Reaction Steps

A carbon tetrachloride (30 mL) solution containing the intermediate from Step B (1.9 g, 10.3 mmol), N-bromosuccinimide (3.56 g, 20 mmol) and AIBN (0.1 g) was heated at reflux for 4 hours. The solution was cooled to room temperature, filtered and concentrated. The residue was purified by silica gel chromatography using a hexanes/EtOAc gradient to give the indicated product. m/z=263.0 (M+H).

Provenance & Evidence