Azobisisobutyronitrile → HCID 67992976, compound

Participants

Reaction Steps

A mixture of the intermediate from Step B (2.336 g, 13.81 mmol), NBS (2.458 g, 13.81 mmol), and AIBN (0.113 g, 0.690 mmol) in 50 mL of CCl4 was refluxed for 1 hour. The mixture was cooled to room temperature, filtered, and concentrated. The residue was purified by silica gel chromatography using a hexanes/EtOAc gradient to give the indicated compound (yellow oil). 1H NMR (CDCl3, 500 MHz) δ 7.72 (1H, s), 3.89 (3H, s), 2.50 (3H, s), 2.29 (3H, s).

Provenance & Evidence