反应详情

Following the procedure as described in EXAMPLE 4 and making non-critical variations to replace 5-bromo-7-(4-methoxybenzyl)imidazol[1,5-a]pyrazin-8(7H)-one with 6-bromo-1H-benzo[d]imidazole hydrochloride salt, 2-(1H-benzo[d]imidazol-5-yl)-4-chlorophenol was obtained as a beige solid in 43% yield (0.110 g): MS (ES+) m/z 245.0 (M+1), 246.9 (M+1).