反应详情

Following the procedure as described in EXAMPLE 4 and making non-critical variations to replace 5-bromo-7-(4-methoxybenzyl)imidazo[1,5-a]pyrazin-8(7H)-one with di-tert-butyl (5-bromo-1,2-benzoxazol-3-yl)imidodicarbonate, di-tert-butyl [5-(2-methoxypyridin-3-yl)-1,2-benzoxazol-3-yl]imidodicarbonate was obtained as a yellow solid in 71% yield (0.471 g): MS (ES+) m/z 441.9 (M+1).