HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(2-iodoethyl)piperidine-1-carboxylate → tert-butyl 4-(2-{[1-(2-methylpropyl)-2-propyl-1H-imidazo[4,5-c]quinolin-7-yl]oxy}ethyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(2-iodoethyl)piperidine-1-carboxylate | HCID 9974426 | — |
| Reactant | 1-(2-methylpropyl)-2-propyl-1H-imidazo[4,5-c]quinolin-7-ol | HCID 136340536 | — |
| Product | tert-butyl 4-(2-{[1-(2-methylpropyl)-2-propyl-1H-imidazo[4,5-c]quinolin-7-yl]oxy}ethyl)piperidine-1-carboxylate | HCID 68972148 | — |
Reaction Steps
The general method described in Part L of Example 2 was used to treat 1-(2-methylpropyl)-2-propyl-1H-imidazo[4,5-c]quinolin-7-ol with tert-butyl 4-(2-iodoethyl)piperidine-1-carboxylate. After the work-up procedure, tert-butyl 4-(2-{[1-(2-methylpropyl)-2-propyl-1H-imidazo[4,5-c]quinolin-7-yl]oxy}ethyl)piperidine-1-carboxylate was isolated as a gray-brown solid and used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365567B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-2555501ea18941fcb8646d5296d5df9b |
| Source note | uspto-grants-2016_06 |