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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 220356Generated: October 30, 2026

1-Bromopentan-2-one → N,N-dicyclopropyl-6-ethyl-1-methyl-4-(4-propylthiazol-2-ylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide

https://huagongshe.com/reaction/220356

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromopentan-2-oneHCID 10057869—
ReactantN,N-dicyclopropyl-6-ethyl-1-methyl-4-thioureido-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamideHCID 58180527—
ProductN,N-dicyclopropyl-6-ethyl-1-methyl-4-(4-propylthiazol-2-ylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamideHCID 58180552—

Reaction Steps

Prepared from N,N-dicyclopropyl-6-ethyl-1-methyl-4-thioureido-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide (example 2B) and 1-bromopentan-2-one using the same procedure as reported for 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08202881B2
Source datasetuspto-grants-2012_06
ORD IDord-1676238eb95c4c13bb120f240bff6a41
Source noteuspto-grants-2012_06