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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 220357Generated: October 27, 2026

1-Bromo-2-butanone → N,N-dicyclopropyl-6-ethyl-4-(4-ethylthiazol-2-ylamino)-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide

https://huagongshe.com/reaction/220357

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-butanoneHCID 13156—
ReactantN,N-dicyclopropyl-6-ethyl-1-methyl-4-thioureido-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamideHCID 58180527—
ProductN,N-dicyclopropyl-6-ethyl-4-(4-ethylthiazol-2-ylamino)-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamideHCID 58180588—

Reaction Steps

Prepared from N,N-dicyclopropyl-6-ethyl-1-methyl-4-thioureido-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide (example 2B) and 1-bromobutan-2-one using the same procedure as reported for 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08202881B2
Source datasetuspto-grants-2012_06
ORD IDord-9b1313f505204ecb86ba388ba46deec0
Source noteuspto-grants-2012_06