Dimethylalumanylium chloride → HCID 86703141, compound

Participants

Reaction Steps

The title compound was prepared in analogy to the procedure described for Step H1, but dimethylaluminium chloride (1M in hexanes) was used instead of trimethylaluminium chloride, and 2-[(5-chloro-1-methyl-6-oxo-1,6-dihydro-pyridin-3-ylamino)-(4-cyano-phenyl)-methyl]-1-isopropyl-1H-pyrrole-3-carboxylic acid ethyl ester (Step AS2) was used instead of 2-[(3-chloro-4-fluoro-phenylamino)-(4-cyano-phenyl)-methyl]-1-isopropyl-1H-pyrrole-3-carboxylic acid ethyl ester to afford the title compound as a brown oil. tR: 2.57 min (HPLC 5); ESI-MS: tR=0.86 min, [M+H]+ 407/409 (LC-MS 1).

Provenance & Evidence