5-Chloro-2-methylaniline → Methyl 5-bromo-2-(((5-chloro-2-methylphenyl)amino)(5-chloropyridin-2-yl)methyl)-1-isopropyl-1H-pyrrole-3-carboxylate

Participants

Reaction Steps

The title compound was prepared in analogy to the procedure described for Step L3 but 5-bromo-2-[(5-chloro-pyridin-2-yl)-hydroxy-methyl]-1-isopropyl-1H-pyrrole-3-carboxylic acid methyl ester (Step BK2) and 5-chloro-2-methyl-phenylamine were used instead of 2-[(4-chloro-phenyl)-hydroxy-methyl]-1-isopropyl-1H-pyrrole-3-carboxylic acid ethyl ester and 3-amino-5-chloro-1-methyl-1H-pyridin-2-one respectively. The title compound was obtained as a yellow-brown solid. ESI-MS: tR=1.59 min, [M+H]+ 510/512/514 (LC-MS 1).

Provenance & Evidence