Water → HCID 66611285, compound

Participants

Reaction Steps

To a solution of phenylmethyl 5-bromo-4-(4-morpholinylmethyl)-2-[(phenylmethyl)oxy]benzoate (may be prepared as described in Description 6; 379 mg, 0.76 mmol) in tetrahydrofuran (6 ml) was added lithium hydroxide (110 mg, 4.58 mmol) followed by water (1.5 ml). The reaction was stirred over the weekend, the solvent removed in vacuo and purified by MDAP to yield the title compound as a solid. 249 mg.

Provenance & Evidence