反应详情

温度

60 °C

To 3-bromo-4-methylphenol (2 g, 10.69 mmol) was added acetyl chloride (0.80 ml, 11.23 mmol). The mixture was heated at 60° C. for one hour, cooled and aluminium chloride (1.426 g, 10.69 mmol) was added. The mixture was heated at 180° C. for 40 minutes, cooled and quenched by stirring with 5N HCl (20 ml) for 20 minutes. The solid was filtered to yield the title compound as a brown solid. 2.45 g.

1. temperaturecooled
2. temperatureThe mixture was heated at 180° C. for 40 minutes
3. temperaturecooled
4. customquenched
5. filtrationThe solid was filtered