Sodium Carbonate → HCID 68060036, compound

Participants

Reaction Conditions

Reaction Steps

Na2CO3 (0.25 ml, 0.25 mmol) and palladium tetrakis (8.61 mg, 7.45 μmol) was added to 5-bromo-4-(4-morpholinylmethyl)-2-[(phenylmethyl)oxy]-N-4-pyridazinylbenzamide (may be prepared as described in Example 1; 60 mg, 0.12 mmol) and (1-methyl-1H-pyrazol-4-yl)boronic acid (18.76 mg, 0.149 mmol) in 1,2-dimethoxyethane (3 ml). The mixture was heated at 120° C. in a microwave for one hour and the solvent was removed in vacuo. The residue was purified by MDAP to yield the title compound as a white solid. 8 mg.

Provenance & Evidence