HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 59471788, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 3-Amino-6-(pyridin-3-yl)pyrazine-2-carboxylic acid | HCID 59472154 | — |
| Product | HCID 59471788 | HCID 59471788 | 97% |
Reaction Steps
To 3-amino-6-(3-pyridyl)pyrazine-2-carboxylic acid (2 g, 9.251 mmol) in MeOH (50 mL) was added conc. H2SO4 (907.3 mg, 493.1 μL, 9.251 mmol) and the mixture heated to reflux for 2 hours. The solvent was removed in vacuo and the mixture neutralised with aq. Na2CO3. The resulting brown solid was collected by filtration and dried (2.08 g, 97% Yield). MS (ES+) 231
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365557B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-ce5b0a768da2492392e8321fc7a5ccf3 |
| Source note | uspto-grants-2016_06 |