3,5-Dimethoxybenzaldehyde → (2Z)-3-(3,5-dimethoxyphenyl)-2-{4-[(8-hydroxyoctyl)oxy]phenyl}prop-2-enenitrile

Participants

Reaction Steps

(2Z)-3-(3,5-dimethoxyphenyl)-2-{4-[(8-hydroxyoctyl)oxy]phenyl}prop-2-enenitrile is prepared starting from {4-[(8-hydroxyoctyl)oxy]phenyl}acetonitrile and the commercial 3,5-dimethoxybenzaldehyde according the same procedure following for example 1 in 68% yield. This material proves chromatographically homogenous and displays spectral characteristics consistent with its assigned structure.

Provenance & Evidence