Methanol → HCID 86725136, compound

Participants

Reaction Steps

1.98 g (8.6 mmol) of 3,5-dinitrobenzoyl chloride are dissolved in 16 mL of toluene and 3 drops of DMF were incorporated. 4 g (8.6 mmol) of (2Z)-2-(1,3-benzodioxol-5-yl)-3-{4-[(11-hydroxyundecyl)oxy]-3-methoxyphenyl}prop-2-enenitrile from example 7, 0.052 g (0.4 mmol) of 4-dimethylaminopyridine and 1.03 mL (13 mmol) of pyridine are added. The mixture is stirred at room temperature for 96 hours. The solution is then heated up to 60° C. and 6.5 ml of MeOH are added. The suspension is stirred at room temperature for 1 hour and at 0° C. for 1 hour. The precipitate is filtered off. Recristallisation of the residue in acetonitrile yielded 5.1 g (90%) of pure 11-{4-[(Z)-2-(1,3-benzodioxol-5-yl)-2-cyanoethenyl]-2-methoxyphenoxy}undecyl 3,5-dinitrobenzoate as yellowish powder.

Provenance & Evidence