HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2204956Generated: October 27, 2026
Triethyl Phosphate → Diethyl 2-(2-(2-iodoethoxy)ethoxy)ethylphosphonate
https://huagongshe.com/reaction/2204956
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethyl Phosphate | HCID 6535 | — |
| Reactant | 1,2-Bis(2-iodoethoxy)ethane | HCID 593436 | — |
| Product | Diethyl 2-(2-(2-iodoethoxy)ethoxy)ethylphosphonate | HCID 86667775 | — |
Reaction Steps
1,2-bis(2-iodoethoxy)ethane (1.0 eq) was mixed with triethyl phosphate (1 eq) then heated to 160° C. for 20 minutes by microwave. The crude mixture was purified by flash chromatography on a COMBIFLASH® system (ISCO) using 85-100% EtOAc/Hex to give diethyl 2-(2-(2-iodoethoxy)ethoxy)ethylphosphonate as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09365506B2 |
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| Source dataset | uspto-grants-2016_06 |
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| ORD ID | ord-e2ef3a2ab54e419e83244077eb9372f3 |
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| Source note | uspto-grants-2016_06 |
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