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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2205027Generated: November 1, 2026

(R)-3-((R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-tert-butoxy-3-oxopropylthio)propane-1,2-diyl dioctanoate → (5R,9R)-1-(9H-fluoren-9-yl)-9-(octanoyloxy)-3,12-dioxo-2,11-dioxa-7-thia-4-azanonadecane-5-carboxylic acid

https://huagongshe.com/reaction/2205027

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-((R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-tert-butoxy-3-oxopropylthio)propane-1,2-diyl dioctanoateHCID 67400188—
Reactant(5R,9R)-9-(dodecanoyloxy)-1-(9H-fluoren-9-yl)-3,12-dioxo-2,11-dioxa-7-thia-4-azatricosane-5-carboxylic acidHCID 67414703—
Product(5R,9R)-1-(9H-fluoren-9-yl)-9-(octanoyloxy)-3,12-dioxo-2,11-dioxa-7-thia-4-azanonadecane-5-carboxylic acidHCID 71294529—

Reaction Steps

The product was prepared from (R)-3-((R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-tert-butoxy-3-oxopropylthio)propane-1,2-diyl dioctanoate by following the procedure described for compound 6.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09365506B2
Source datasetuspto-grants-2016_06
ORD IDord-cdd2f098c38649188feebbfab63fa26f
Source noteuspto-grants-2016_06