HuagongsheHuagongshe Chemistry Print Report · For research reference only
Decanoyl chloride → (R)-3-((R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-tert-butoxy-3-oxopropylthio)propane-1,2-diyl bis(decanoate)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Decanoyl chloride | HCID 66982 | — |
| Reactant | (R)-tert-butyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-((R)-2,3-dihydroxypropylthio)propanoate | HCID 10412572 | — |
| Reactant | (R)-3-((R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-tert-butoxy-3-oxopropylthio)propane-1,2-diyl didodecanoate | HCID 66613539 | — |
| Product | (R)-3-((R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-tert-butoxy-3-oxopropylthio)propane-1,2-diyl bis(decanoate) | HCID 67402798 | — |
Reaction Steps
The product was prepared from (R)-tert-butyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-((R)-2,3-dihydroxypropylthio)propanoate (10, 1 eq) and decanoyl chloride (3.7 eq) by following the procedure described for compound 11.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365506B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-3e5d7566d469448a827e57a49fc3e0c0 |
| Source note | uspto-grants-2016_06 |