HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethoxyphenylboronic acid → HCID 86718106, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethoxyphenylboronic acid | HCID 2734351 | — |
| Reactant | Methyl 3-chloro-2-phenylquinoxaline-6-carboxylate | HCID 77231183 | — |
| Product | HCID 86718106 | HCID 86718106 | 43% |
Reaction Steps
The ester product was obtained via a Suzuki coupling reaction using the method previously shown in Example 13, Step 6, with methyl 3-chloro-2-phenylquinoxaline-6-carboxylate (100 mg, 0.34 mmol, 1.00 equiv) and 4-ethoxyphenylboronic acid (61 mg, 0.37 mmol, 1.10 equiv) As reactants. Purification via silica gel column (ethyl acetate/petroleum ether (1:5)) yielded 55 mg (43%) of methyl 3-(4-ethoxyphenyl)-2-phenylquinoxaline-6-carboxylate as a yellow powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09370522B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-907b6c8b3cc64a99b73b5ad3ae0e7c27 |
| Source note | uspto-grants-2016_06 |