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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2205105Generated: November 3, 2026

4-Ethoxyphenylboronic acid → HCID 86718106, compound

https://huagongshe.com/reaction/2205105

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Ethoxyphenylboronic acidHCID 2734351—
ReactantMethyl 3-chloro-2-phenylquinoxaline-6-carboxylateHCID 77231183—
ProductHCID 86718106HCID 8671810643%

Reaction Steps

The ester product was obtained via a Suzuki coupling reaction using the method previously shown in Example 13, Step 6, with methyl 3-chloro-2-phenylquinoxaline-6-carboxylate (100 mg, 0.34 mmol, 1.00 equiv) and 4-ethoxyphenylboronic acid (61 mg, 0.37 mmol, 1.10 equiv) As reactants. Purification via silica gel column (ethyl acetate/petroleum ether (1:5)) yielded 55 mg (43%) of methyl 3-(4-ethoxyphenyl)-2-phenylquinoxaline-6-carboxylate as a yellow powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09370522B2
Source datasetuspto-grants-2016_06
ORD IDord-907b6c8b3cc64a99b73b5ad3ae0e7c27
Source noteuspto-grants-2016_06