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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2205106Generated: November 2, 2026

3,4-Dimethoxyphenylboronic acid → HCID 86718107, compound

https://huagongshe.com/reaction/2205106

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Dimethoxyphenylboronic acidHCID 2734702—
ReactantMethyl 3-bromo-2-phenylquinoxaline-6-carboxylateHCID 86667202—
ProductHCID 86718107HCID 8671810744.6%

Reaction Steps

The ester product was obtained via a Suzuki coupling reaction using the method previously shown in Example 13, Step 6, with methyl 3-bromo-2-phenylquinoxaline-6-carboxylate (100 mg, 0.29 mmol, 1.00 equiv) and 3,4-dimethoxyphenylboronic acid (80 mg, 0.44 mmol, 1.50 equiv) as reactants. Purification by Prep-TLC (silica gel) yielded 50 mg (44%) of 3-(3,4-dimethoxyphenyl)-2-phenylquinoxaline-6-carboxylic acid as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09370522B2
Source datasetuspto-grants-2016_06
ORD IDord-b69732a470454dd4acbb5d0d7f630e3b
Source noteuspto-grants-2016_06