(Naphthalen-2-yl)boronic acid → HCID 86718108, compound

Participants

Reaction Steps

The ester product was obtained via a Suzuki coupling reaction using the method previously shown in Example 13, Step 6, with methyl 3-chloro-2-phenylquinoxaline-6-carboxylate (100 mg, 0.34 mmol, 1.00 equiv) and naphthalen-2-yl boronic acid (63 mg, 0.37 mmol, 1.10 equiv). Purification via silica gel column (ethyl acetate/petroleum ether (1:20)) yielded 62 mg (47%) of methyl 3-(naphthalen-2-yl)-2-phenylquinoxaline-6-carboxylate as a yellow solid.

Provenance & Evidence