HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Pyridin-4-yl)boronic acid → HCID 86718111, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Pyridin-4-yl)boronic acid | HCID 2734379 | — |
| Reactant | Methyl 3-bromo-2-phenylquinoxaline-6-carboxylate | HCID 86667202 | — |
| Product | HCID 86718111 | HCID 86718111 | 31.6% |
Reaction Steps
The product was obtained via a Suzuki coupling reaction using the method previously shown in Example 20, Step 3, with methyl 3-bromo-2-phenylquinoxaline-6-carboxylate (100 mg, 0.29 mmol, 1.00 equiv) and pyridin-4-yl boronic acid (54 mg, 0.44 mmol, 1.50 equiv) as reactants. Purification by Prep-TLC (silica gel) yielded 30 mg (30%) of 2-phenyl-3-(pyridin-4-yl)quinoxaline-6-carboxylic acid as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09370522B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-e377ce8d85914dc0a997f3f9d1573e45 |
| Source note | uspto-grants-2016_06 |