4-Cyanophenylboronic acid → HCID 86718112, compound

Participants

Reaction Steps

The ester product was obtained via a Suzuki coupling reaction using the method previously shown in Example 13, Step 6, with methyl 3-chloro-2-phenylquinoxaline-6-carboxylate (100 mg, 0.33 mmol, 1.00 equiv) and 4-cyanophenylboronic acid (74 mg, 0.50 mmol, 1.50 equiv) as reactants. Purification via silica gel column (ethyl acetate/petroleum ether (1:20 to 1:10)) afforded 90 mg (73%) of methyl 3-(4-cyanophenyl)-2-phenylquinoxaline-6-carboxylate as a yellow solid.

Provenance & Evidence