(4-Bromophenyl)boronic acid → HCID 86718118, compound

Participants

Reaction Steps

The product was obtained via a Suzuki coupling reaction using the method previously shown in Example 20, Step 3, using methyl 3-bromo-2-phenylquinoxaline-6-carboxylate (100 mg, 0.29 mmol, 1.00 equiv) and 4-bromophenylboronic acid (67.9 mg, 0.34 mmol, 1.50 equiv) as reactants. Purification via silica gel column (dichloromethane/methanol (5:1)) yielded 14 mg (10%) of 3-(4-bromophenyl)-2-phenylquinoxaline-6-carboxylic acid as a light yellow solid.

Provenance & Evidence