Boronic acid, (4-ethylphenyl)- → HCID 86718119, compound

Participants

Reaction Steps

The product was obtained via a Suzuki coupling reaction using the method previously shown in Example 20, Step 3, using methyl 3-bromo-2-phenylquinoxaline-6-carboxylate (100 mg, 0.29 mmol, 1.00 equiv) and 4-ethylphenylboronic acid (62.3 mg, 0.42 mmol, 1.50 equiv) as reactants. Purification via silica gel column (dichloromethane/methanol (5:1)) yielded 52 mg (49%) of 3-(4-ethylphenyl)-2-phenylquinoxaline-6-carboxylic acid as a white solid.

Provenance & Evidence