HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Carboxyphenylboronic Acid → HCID 86718121, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Carboxyphenylboronic Acid | HCID 312183 | — |
| Reactant | Methyl 3-bromo-2-phenylquinoxaline-6-carboxylate | HCID 86667202 | — |
| Product | HCID 86718121 | HCID 86718121 | 19.6% |
Reaction Steps
The product was obtained via a Suzuki coupling reaction using the method previously shown in Example 20, Step 3, using methyl 3-bromo-2-phenylquinoxaline-6-carboxylate (100 mg, 0.29 mmol, 1.00 equiv) and 4-carboxyphenylboronic acid (73 mg, 0.44 mmol, 1.50 equiv) as reactants. Purification by prep-TLC yielded 21 mg (19%) of 3-(4-carboxyphenyl)-2-phenylquinoxaline-6-carboxylic acid as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09370522B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-2ec446ce67d14ebc91d052a413d21ee4 |
| Source note | uspto-grants-2016_06 |